Beta-Blocker Withdrawal (Propranolol, Metoprolol)
Compiled from cited sources · not yet medically reviewedUpdated 3 sources
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For information only, not medical advice. Talk to a doctor before stopping or changing any medication. Medical disclaimer
⚠ Medical warning
Stopping this medicine suddenly can be dangerous for your heart and blood pressure. Don’t stop without talking to your prescriber. Call 911 for chest pain, a racing heart, or a sudden severe headache.
Quick answer
Beta-blocker labels warn that after abrupt stopping, people have had worsening angina and, in some cases, heart attacks. The propranolol label says to reduce gradually over at least a few weeks; the metoprolol succinate label says over 1 to 2 weeks. The NHS says that after stopping propranolol, side effects can last up to 1 week. Because heart disease may be undiagnosed, this applies even if you take it for blood pressure, anxiety or migraine.
Beta-blockers withdrawal timeline at a glance
When did you last use or take it?
⚠ Medical warning (read before using this)
Stopping this medicine suddenly can be dangerous for your heart and blood pressure. Don’t stop without talking to your prescriber. Call 911 for chest pain, a racing heart, or a sudden severe headache.
This places the typical ranges from this article's sources on your date. It is not a prediction or a diagnosis, and being past a phase does not mean symptoms or risks are over.
A rough guide from published sources, not medical advice. Everyone is different.
| Phase | When | What you may feel | Severity | Red flags |
|---|---|---|---|---|
| Early rebound | The first days after a sudden stop | Fast or pounding heartbeat; Anxiety, tremor; Return of the symptoms it treated (such as blood pressure or migraine) | Moderate | Chest pain, a racing or pounding heart, or a severe headache with very high blood pressure (call 911) |
| Heart risk window | Days to about a week after stopping (NHS: side effects up to 1 week) | Chest pain (angina); Higher blood pressure | Can be life-threatening | Chest pain or pressure (call 911); Signs of a heart attack or stroke |
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Symptoms, phase by phase
The propranolol label says there have been reports of worsening angina and, in some cases, heart attack after abrupt discontinuation, and that abrupt withdrawal may worsen symptoms of an overactive thyroid, including thyroid storm. The metoprolol label adds that because coronary artery disease is common and may be unrecognized, it shouldn’t be stopped abruptly even in people treated only for high blood pressure. The NHS says stopping propranolol suddenly may make your health problem worse, and side effects of stopping can last up to a week.
Early rebound: The first days after a sudden stop
- Fast or pounding heartbeat
- Anxiety, tremor
- Return of the symptoms it treated (such as blood pressure or migraine)
Heart risk window: Days to about a week after stopping (NHS: side effects up to 1 week)
- Chest pain (angina)
- Higher blood pressure
What makes withdrawal longer or shorter
- Heart disease. The risk is greatest if you have angina or coronary disease, even if undiagnosed.
- How long you’ve taken it. The NHS says extra symptoms are more likely after long-term use.
- Thyroid problems. Abrupt stops can trigger thyroid storm in people with an overactive thyroid.
- Clonidine. If you take both, your doctor needs to plan the order of stopping.
When to see a doctor or get help now
- Before stopping, even if you take it for anxiety or migraine.
- Call 911 for chest pain, shortness of breath or a pounding heart that won’t settle.
- Before surgery; labels say beta-blockers usually shouldn’t be routinely stopped beforehand.
Not sure where to start? Call SAMHSA’s free, confidential helpline at 1-800-662-4357, 24/7. See Get Help.
Tapering
The propranolol label says to reduce over at least a few weeks; the NHS says your doctor will usually reduce it over 1 to 2 weeks; the metoprolol succinate label says 1 to 2 weeks. We don’t publish dose-by-dose schedules. Your prescriber should set your plan, and adjust it if symptoms appear.
Tips for getting through it
- Keep taking it until your doctor’s plan says otherwise
- Check pulse or blood pressure at home if advised
Frequently asked questions
Can I stop propranolol if I only take it for anxiety?
Talk to your doctor first. The NHS says stopping suddenly can cause extra side effects, and labels warn of heart risks.
How long does propranolol withdrawal last?
The NHS says side effects can last up to a week after stopping.
Is metoprolol withdrawal dangerous?
It can be for people with heart disease. The label says to reduce over 1 to 2 weeks.
Next steps
- Track your dayEnter when you stopped to see where you are on the timeline
- Combine timelinesAdd other things you are stopping and see them on one chart
- Talk to othersAsk questions on our community forum (peer support, not medical advice)
- Read nextClonidine Withdrawal: Rebound Blood Pressure
- Get helpFree, confidential helplines and when to see a doctor
Talk to others going through it. Share your experience or ask questions on the Antidepressants & Other Prescriptions board in our community forum. Planning to stop? See the Tapering & Talking to Your Doctor board, and talk to a doctor before you stop. Forum posts are personal experiences, not medical advice. Please read the community guidelines.
Related timelines
- Clonidine Withdrawal: Rebound Blood Pressure
- Caffeine Withdrawal Timeline: Day by Day
- Benzo Withdrawal Timeline: Short- vs Long-Acting
Sources
- FDA label: Inderal LA (propranolol) (DailyMed)
- FDA label: Metoprolol succinate extended-release tablets (DailyMed)
- NHS: Propranolol
Last reviewed: October 25, 2026. Researched and written by Withdrawal Timelines from the cited sources. This article has not yet been reviewed by a medical professional. See How We Review and our Medical Disclaimer. This is general information, not medical advice.
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