Skip to content
Join the forum

Protracted Withdrawal: When Symptoms Last Months

Published by Joseph, EditorCompiled from cited sources · not yet medically reviewedUpdated 5 sources

Illustration of a wooden window looking out on a calm teal lake, with a tree half bare in winter and half budding with spring leaves

Need help now? SAMHSA’s National Helpline is free, confidential and open 24/7 in English and Spanish: 1-800-662-4357. In a mental health crisis, call or text 988. In an emergency, call 911.

For information only, not medical advice. Talk to a doctor before stopping or changing any medication. Medical disclaimer

Quick answer

Protracted withdrawal means withdrawal-type symptoms that persist, evolve or appear well past the expected acute withdrawal window. SAMHSA says symptoms can be felt for weeks, months, and sometimes years, and commonly include anxiety, sleep problems, poor memory and concentration, fatigue, low mood, irritability, cravings and anhedonia (finding it hard to feel pleasure). It is also called post-acute withdrawal syndrome (PAWS).

It’s not well studied. SAMHSA says research is limited, especially for substances other than alcohol, and there’s no agreed definition, so no standard timeframe exists. Not everyone gets it, and it varies in intensity. For benzodiazepines, the FDA describes a protracted withdrawal syndrome beyond 4 to 6 weeks that may last up to 12 months. For antidepressants, NICE says withdrawal occasionally lasts several months. SAMHSA says symptoms don’t last forever and can be managed.

Protracted withdrawal at a glance

When did you last use or take it?

This places the typical ranges from this article's sources on your date. It is not a prediction or a diagnosis, and being past a phase does not mean symptoms or risks are over.

A rough guide from published sources, not medical advice. Everyone is different.

PhaseWhenWhat you may feelSeverityRed flags
Acute withdrawalDays to a few weeks, depending on the substance (SAMHSA: alcohol 5 to 7 days, opioids 4 to 10 days, benzodiazepines 1 to 4 weeks)The usual withdrawal symptoms for that substance; Often the opposite of the drug’s effects; Gradually resolveModerateStopping benzodiazepines abruptly can cause seizures: get medical help
Protracted phaseWeeks to months after acute withdrawal; for benzodiazepines the FDA says beyond 4 to 6 weeks and up to 12 monthsAnxiety, irritability, low mood; Sleep problems; Poor memory and concentration, fatigue; Cravings; Anhedonia (finding it hard to enjoy things)ModerateSuicidal thoughts: call or text 988 now
Long tail (some people)Beyond a year in some reports; SAMHSA notes alcohol sleep changes can persist 1 to 3 yearsSymptoms that wax and wane; Sleep abnormalities after alcohol; Gradual improvement with timeMildNew or worsening symptoms: get checked for other causes

Print a daily symptom log for this timeline · My quit tracker

Symptoms, phase by phase

SAMHSA lists these possible protracted withdrawal symptoms: anxiety; sleep difficulties; problems with short-term memory; persistent fatigue; difficulty concentrating, focusing and making decisions; alcohol or drug cravings; impaired executive control (impulse control, problem solving); anhedonia; low mood or depression; irritability; unexplained physical complaints; and reduced interest in sex. Some people feel clearer for the first month or two and then have symptoms again.

Acute withdrawal: Days to a few weeks, depending on the substance (SAMHSA: alcohol 5 to 7 days, opioids 4 to 10 days, benzodiazepines 1 to 4 weeks)

  • The usual withdrawal symptoms for that substance
  • Often the opposite of the drug’s effects
  • Gradually resolve

Protracted phase: Weeks to months after acute withdrawal; for benzodiazepines the FDA says beyond 4 to 6 weeks and up to 12 months

  • Anxiety, irritability, low mood
  • Sleep problems
  • Poor memory and concentration, fatigue
  • Cravings
  • Anhedonia (finding it hard to enjoy things)

Long tail (some people): Beyond a year in some reports; SAMHSA notes alcohol sleep changes can persist 1 to 3 years

  • Symptoms that wax and wane
  • Sleep abnormalities after alcohol
  • Gradual improvement with time

Protracted withdrawal by substance

SubstanceAcute withdrawal (SAMHSA)What’s known about longer symptoms
Alcohol5 to 7 daysBest documented. Anxiety, irritability, low mood, fatigue, insomnia and poor concentration. Sleep abnormalities can persist 1 to 3 years in sleep studies; case reports suggest 2 years or longer (SAMHSA). Alcohol timeline
Benzodiazepines1 to 4 weeks; 3 to 5 weeks with taperingFDA: protracted syndrome beyond 4 to 6 weeks, lasting weeks to as long as 12 months: anxiety, cognitive problems, depression, insomnia, crawling skin (formication), weakness, tremor, twitches, pins and needles, tinnitus. Benzo timeline
Opioids4 to 10 days (methadone 14 to 21)Anxiety, depression and sleep problems for weeks or months; fatigue, irritability, feeling emotionally blunted (SAMHSA). Opioid timeline
Cannabis5 daysSleep difficulties and strange dreams lasted at least 45 days, the longest any reviewed study ran (SAMHSA). Weed timeline
Stimulants1 to 2 weeksProblems with impulse control and executive function can persist well into recovery from methamphetamine and cocaine (SAMHSA). Meth timeline
AntidepressantsUsually 1 to 2 weeks (NICE)Occasionally several months (NICE); the Royal College of Psychiatrists says sometimes more than a year. Antidepressant guide

Is it withdrawal, rebound, or the original problem?

This is often the hardest question. SAMHSA describes, for benzodiazepines, three different things:

  • Rebound: the intensified return of acute withdrawal symptoms, typically the opposite of the drug’s effects (anxiety, insomnia, restlessness). It tends to ease in a few weeks.
  • Re-emergence: the return of symptoms you had before starting, at the same level. These don’t fade with time and may point to a condition that needs treatment.
  • Protracted withdrawal: symptoms that are new to you and typically wax and wane, gradually easing with time.

The FDA also notes the difficulty of telling benzodiazepine withdrawal apart from re-emerging symptoms. SAMHSA says some protracted symptoms can look like depression, anxiety disorders or the effects of a head injury, so it recommends assessment and reassessment for other conditions, including depression and suicidal thoughts.

What makes it more or less likely

  • Which substance. Each drug class affects the brain differently, so symptoms are similar but not identical (SAMHSA).
  • Stopping quickly. In FDA reports, some people had withdrawal lasting many months after a benzodiazepine was stopped abruptly or reduced too quickly. NICE says antidepressant withdrawal can be severe, particularly after stopping suddenly.
  • Longer use and higher doses. The NHS says lasting antidepressant withdrawal may be more likely the longer you’ve taken them or the higher the dose. Most FDA benzodiazepine reports involved use for months to years.
  • Individual variation. SAMHSA says some people have no symptoms after acute withdrawal and others have lingering ones; it isn’t possible to predict who.

When to see a doctor or get help now

  • Talk to a doctor if symptoms are lasting, getting worse or affecting daily life. They can check for other causes, such as depression or another health problem.
  • If you’re tapering a prescription medicine and symptoms are severe, the FDA (benzodiazepines) and NICE (antidepressants) both describe pausing, or going back to the previous dose and then reducing more slowly. Discuss this with your prescriber.
  • Call 911 for a seizure, confusion or hallucinations.
  • Call or text 988 if you have thoughts of suicide or self-harm. For treatment referrals, call the SAMHSA National Helpline at 1-800-662-4357.

See Get Help for more support options.

Tapering

For prescription medicines, a gradual, individual taper is the main way to reduce withdrawal. The FDA says there’s no standard benzodiazepine taper that suits everyone. NICE says antidepressant withdrawal may take weeks or months to complete. For opioids, SAMHSA suggests methadone or buprenorphine treatment can be considered when protracted symptoms are too powerful, and for alcohol it says medicines such as acamprosate might relieve some protracted symptoms like anxiety and poor sleep. We don’t publish dose-by-dose schedules; a prescriber can tailor a plan.

Tips for getting through it

These come from SAMHSA’s advice to treatment providers:

  • Expect recovery to be a process: it’s normal not to feel fully recovered in the first weeks and months
  • Focus on small improvements, and don’t be discouraged if symptoms come back for a while
  • Keep a regular sleep routine: same bed and wake times, exercise early in the day, less caffeine, and no late-afternoon naps
  • Stay physically and mentally active, and use to-do lists and daily routines for memory and concentration problems
  • Don’t try to make up for lost time by overbooking yourself; extra stress can make symptoms worse
  • Consider a mutual support group; it may take a few tries to find one that fits

Frequently asked questions

Is protracted withdrawal the same as PAWS?

Yes, they’re names for the same idea. SAMHSA lists post-acute withdrawal syndrome as one of several terms for protracted withdrawal. See our PAWS page for more.

How long does protracted withdrawal last?

There’s no standard timeframe because it isn’t well studied. SAMHSA describes weeks, months and sometimes years. The FDA says protracted benzodiazepine withdrawal may last up to 12 months.

Is protracted withdrawal a recognized diagnosis?

Not formally. SAMHSA notes there’s no agreed definition, which is why the DSM doesn’t include a protracted withdrawal diagnosis.

Will it go away?

SAMHSA says symptoms will not last forever and can be managed, and that in many cases substance-related brain changes reverse with long-term abstinence.

Can it start after I already felt better?

Yes. SAMHSA says some people have a clear first month or two and then develop symptoms again, and some benzodiazepine users feel fine for a while before becoming very anxious.

Next steps

Talk to others going through it. Share your experience or ask questions on the Check-ins board in our community forum. Forum posts are personal experiences, not medical advice. Please read the community guidelines.

Sources

  1. SAMHSA Substance Abuse Treatment Advisory: Protracted Withdrawal, Vol 9 Issue 1, July 2010 (HHS Publication SMA10-4554)
  2. FDA: FDA requiring Boxed Warning updated to improve safe use of benzodiazepine drug class, 2020
  3. NICE guideline NG222: Depression in adults, recommendations 1.4.12 to 1.4.21 (stopping antidepressant medication), 2022
  4. NHS: Antidepressants (section: How long antidepressant withdrawal symptoms last), last reviewed 12 June 2025
  5. Royal College of Psychiatrists: Stopping antidepressants

Last reviewed: October 29, 2026. Researched and written by Withdrawal Timelines from the cited sources. This article has not yet been reviewed by a medical professional. See How We Review and our Medical Disclaimer. This is general information, not medical advice.

More timelines

View all

view all